DLL3 and neuroendocrine carcinoma: A DLL3-targeted antibody-drug conjugate linked to a pyrrolobenzodiazepine dimer toxin, Rovalpituzumab tesirine, achieved a 17% ORR in 35 DLL3-overexpressing NEN (NEC and NET) patients (including UPO-NEN) in a phase I/II trial.