Most of the time, a double stain with p63 (a nuclear marker of the basal layers) and AMACR (alpha-methylacyl-CoA racemase, a cytoplasmatic marker of tumor cells) will be co-expressed in IDC-P (see Figure 1) and, therefore, together with morphology, guide the pathologist toward the right diagnosis [4]. The gene discussed is AMACR; the disease is neoplasm.