TP53 and lung adenocarcinoma: TR107 (stage IIIA, squamous-cell carcinoma, 77-year-old male with history of bladder carcinoma, former smoker) has a TP53 missense mutation c.743G>A characterized as pathogenic with moderated impact on protein function and reported in Li–Fraumeni syndrome, lung adenocarcinoma, and squamous-cell lung carcinoma.