The authors attempted to evaluate the HER2 staining in BC based on H&E images only and reported success in HER2 expression staging (AUC 0.9202 ± 0.01, precision 0.922 ± 0.01, sensitivity 0.876 ± 0.01, and specificity 0.959 ± 0.02 over five-fold cross-validation with a 95% confidence interval (CI)) [107]. Here, ERBB2 is linked to breast cancer.