Circ_0020123 is particularly interesting for the multiple interaction pathways in which it is involved in lung cancer and appears to be capable of promoting cell proliferation and migration on tumor growth in vivo, acting on the THBS2/miR590-5p axis [92] and favoring cisplatin resistance in NSCLC cells by targeting miR-14-3p [93]. The gene discussed is THBS2; the disease is non-small cell lung carcinoma.