Circ_0020123 is particularly interesting for the multiple interaction pathways in which it is involved in lung cancer and appears to be capable of promoting cell proliferation and migration on tumor growth in vivo, acting on the THBS2/miR590-5p axis [92] and favoring cisplatin resistance in NSCLC cells by targeting miR-14-3p [93]. This evidence concerns the gene THBS2 and lung carcinoma.