A fresh study revealed that patients with locally advanced (p < 0.0001) or metastatic (p < 0.0001) iCCA had higher serum levels of carcinoembryonic antigen (CEA) (cutoff value: 5 U/mL) and CA19-9 (cutoff value: 37 U/mL) than patients with earlier stage liver-confined disease [27]. Here, CEACAM5 is linked to infantile convulsions and choreoathetosis.