CRP and anemia: In order to verify if the exposures, susceptibilities, AKI cause and several biological parameters are indeed independent factors that increase the risk of AKD development, we performed a logistic regression with AKD as the dependent variable and the following factors as independent ones: sex, age, baseline creatinine, serum proteins, C reactive protein, sodium, ICU admission, sepsis, critical illness, nephrotoxins exposure, neoplasia, anaemia, heart failure, arterial hypertension, stem cell transplantation and AKI cause (as seen in Table 3).