In order to verify if the exposures, susceptibilities, AKI cause and several biological parameters are indeed independent factors that increase the risk of AKD development, we performed a logistic regression with AKD as the dependent variable and the following factors as independent ones: sex, age, baseline creatinine, serum proteins, C reactive protein, sodium, ICU admission, sepsis, critical illness, nephrotoxins exposure, neoplasia, anaemia, heart failure, arterial hypertension, stem cell transplantation and AKI cause (as seen in Table 3). This evidence concerns the gene CRP and Hypertension.