A more recent study by Bakow et al. [59] found that the incidence rate of recurrent venous thrombosis in APS patients with single aPL positivity was comparable to that of patients without APS who had previously experienced venous thrombosis and did not vary depending on the anticoagulation regimen (DOACs or VKAs), suggesting that single-positive APS patients may not require extended anticoagulation with VKAs. Here, FASLG is linked to autoimmune polyendocrinopathy.