Xn exposure at 10 μM for 24 h caused a significant decrease in CD73 activity (42.7 ± 1.15 vs. 23.6 ± 4.0 nmol Pi/mg protein·min, p < 0.05), while the cytosolic activity of the enzyme remains unaltered by the treatment in C6 glioma cells, as can be observed in Figure 6A and Figure 6C, respectively. This evidence concerns the gene NT5E and central nervous system cancer.