Of note, DQ2+/DQ8+ infants featuring delayed introduction of gluten into the diet from 4–6 months to 12 months of age showed a positive effect on prolonging gluten, as well as lower incidence of CeD autoimmunity, with an overall relative absence of the phylum Bacteroidetes and a concomitant high abundance of Firmicutes, with a microbiota quite different than that of adults even at 2 years of age [148]. The gene discussed is TOR1A; the disease is cranioectodermal dysplasia.