An age- and sex-adjusted multivariate analysis showed that the only cytokine associated with increased mortality in patients with HF was MCP-1 (OR 1.01, 95% CI: 1.01–1.02), as well as its combination with IL-6 (OR 1.01, 95% CI: 1.01–1.02). This evidence concerns the gene CCL2 and hydrops fetalis.