The main signal pathways involved in differential proteins include: motor proteins, protein digestion and absorption, focal adhesion, human papillomavirus infection, ECM-receptor interaction, PIK-Akt signaling pathway, adrenergic signaling in cardiomyocytes, cardiac muscle contraction, dilated cardiomyopathy, hypertrophic cardiomyopathy, and so on. This evidence concerns the gene AKT1 and human papilloma virus infection.