Viability of pancreatic cancer cell lines with different KRAS mutational status, namely MiaPaCa (KRAS G12C), Panc-1 (KRAS G12D), and BxPC3 (KRAS wild-type), was analyzed using Celltiter-Glo luminescent assay, which relies on the quantitation of ATP present in the cells as the measure of metabolically active cells. The gene discussed is KRAS; the disease is pancreatic neoplasm.