There is a notable variation in oncogenic KRAS allelic distribution across different tumor types; while G12C is more prevalent in KRAS mutant adenocarcinomas of the lung (13.6%), G12D, G12V, and G12R represent the most common oncogenic KRAS variants detected in pancreatic cancers (37.0%, 28.2%, and 12.7%, respectively), while G12C is found in only 1.1% of cases [51]. The gene discussed is KRAS; the disease is familial pancreatic carcinoma.