CP and cancer: These experimental strategies suggest that the mechanism of resistance to CP from the perspective of the glucose metabolism suggests that SKOV3/DDP cells (cancer cell lines) exhibit decreased dependence on aerobic glycolysis and increased demand for glucose; thus, resetting the redox balance through the overexpression of the key glucose enzyme, glucose 6-phosphate dehydrogenase (G6PD), of the pentose phosphate pathway to eliminate the cytotoxicity of highly elevated ROS [38].