TBP and giardiasis: Considering the significant variation observed in the amino acid sequences of TBPs from early branching protists [13,14,15,16], like the one studied here, and the low mutation rate found in this protein and other transcription factors [17,18], we suggest TBP as a promising candidate for targeted therapy against giardiasis since multiple crystallographic studies have determined that the entire surface of the TBP interacts with other transcription factors [15].