GCLC and neoplasm: In response to LT HFD, tumour reduced glutathione (GSH) content rose significantly (LT HFD = 0.015 ± 0.002 vs. ST HFD = 0.007 ± 0.001 mmol, p = 0.1, Figure 6G) while glutamate-cysteine ligase catalytic subunit (Gclc) expression was significantly reduced (LT HFD = 0.80 ± 0.06, p = 0.0476 vs. ST HFD = 1.04 ± 0.14, Figure 6H).