The DE upregulated miRNAs (out of 191, only 20 miRNAs used in pathway analysis) in the 8-week S. gordonii infection involved in the pluripotency of stem cells pathways, MAPK-signaling pathway, Axon guidance, Wnt signaling pathway, Arrhythmogenic right ventricular cardiomyopathy, mTOR signaling pathway, and thyroid hormone signaling pathway. The gene discussed is TG; the disease is arrhythmogenic right ventricular cardiomyopathy.