WNK2 and cancer: The KEGG pathway analysis revealed that the upregulated genes were significantly enriched in mitogen-activated protein kinase (MAPK) signaling, pathways in cancer, WNT (Wingless and Int-1) signaling pathway, Focal adhesion, TGF-beta signaling pathway, and Ubiquitin mediated proteolysis are commonly identified in DE miRNAs of 8 and 16 weeks (Figure 2C).