Strategies for managing cancer using combinations of multiple phytochemicals (“Multifocal Signal Modulation Therapy”) were proposed by McCarty (2021) [24], and a comprehensive review of how the pro-apoptotic action of NF-kB-inhibitory phytochemicals may act as a pivotal defense against pathological inflammation and disease is described in Martins (2006) [10]. The gene discussed is NFKB1; the disease is cancer.