Spice flavorings and nuclear-factor kappa beta Processes that involve NF-kB have emerged as very important mediators of disease- or trauma-associated inflammation, particularly as a major characteristic of syndromes with increased incidence among elderly populations such as cancer, atherosclerosis, cardiovascular disorders, diabetes, allergies, asthma, Alzheimer’s disease, osteoporosis, and many forms of autoimmunity [5,6]. This evidence concerns the gene NFKB1 and cancer.