Frontal cortex:Hypomethylation in 5 CpGs located further from TSS in intron 1 in PD-GBA1 compared to controlsHypomethylation in 2 CpGs in intron 1 in PD-GBA1 compared to idiopathic PDNo significant differences in any CpGs located close to TSS in intron 1 or in the promoterPutamen: No significant differences in intron 1 or the promoterSubstantia nigra: 1 CpG in the promoter hypomethylated in idiopathic PD compared to both controls and PD-GBA1No significant differences in intron 1. The gene discussed is GBA1; the disease is Parkinson disease.