NLRP3 and colorectal carcinoma: In a pan-cancer analysis of NLRP3 inflammasome methylation, it was found that in sporadic CRC, seven NLRP3 inflammasome-related genes (i.e., CARD8, ATAT1, CD36, NLRC3, NLRP3, PSTPIP1, and TXNIP) showed altered DNA methylation statuses.