VSIG4 and neoplasm: By analyzing VSIG4 mRNA expression in a published single-cell RNA-seq (scRNA-seq) dataset comprising tumor-derived and peripheral immune populations from 7 non-small cell lung cancer (NSCLC) patients [11], we found that VSIG4 is localized to tumor-associated myeloid populations within the tumor microenvironment and is absent in every other cellular population in the TME and the periphery (Figure 1A).