Recent advances in genome-wide association studies (GWASs) from the published projects of the CKDGen Consortium have unveiled numerous genetic variants associated with CKD and kidney function-related traits, including biomarkers used to quantify kidney function, such as glomerular filtration rate estimated from creatinine levels (eGFRcrea), glomerular filtration rate estimated from serum cystatin C levels (eGFRcys), and blood urea nitrogen (BUN), as well as the urine albumin-to-creatinine ratio (UACR), which serves as a measure of kidney damage [4,5,6]. Here, CST3 is linked to chronic kidney disease.