Sex stratification of the study subjects did not show significant differences in the concentration of TNF-α in the analyzed cohorts, although average values were higher in FD patients of both sexes compared to healthy controls (control males: 7.23 ± 0.88 pg/mL; FD males: 15.25 ± 2.70 pg/mL; control females: 6.66 ± 0.98 pg/mL; FD females: 9.23 ± 0.94 pg/mL). The gene discussed is TNF; the disease is Fabry disease.