According to papers [58,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152], RJ has many beneficial effects on cognition and AD pathology, including the improvement of memory, neuroprotection and regulation of neurotrophins, regulation of neurotransmission, regulation of brain energy metabolism, protection against oxidative stress and neuroinflammation, reduction of apoptosis, attenuation of Aβ-induced neurotoxicity, and improvement of hormonal and metabolic abnormalities associated with cognitive impairment (see Figure 3). This evidence concerns the gene BDNF and Alzheimer disease.