Formation of the Annexin A6/LDL receptor-related protein 1/thrombospondin 1 (ANXA6, SE = 3.9/LRP1, SE = 2.5/THBS1, SE = 6.8) complex was restricted to CAFs and required physio-pathologic culture conditions that improved tumor cell survival and migration [58]. The gene discussed is THBS1; the disease is neoplasm.