The described inhibition of CYP1A2 and CYP2C8 by niclosamide can have distinct effects on other drugs applied for the therapy of viral infections (e.g., CYP1A2-mediated metabolism of clopidogrel, clozapine, and theophylline and CYP2C8-mediated metabolism of ibuprofen, loperamide, morphine, pioglitazone, remdesivir, repaglinide, and rosiglitazone) [36]. This evidence concerns the gene CYP2C8 and viral infectious disease.