This could happen since in a recent case report of a 58-year-old Caucasian with advanced CKD, elevated liver enzymes, and recurrent pulmonary infection and a negative family history, the renal biopsy evaluation revealed KIN, and the genetic testing confirmed a nonsense mutation in exon 2 and a deletion in exon 12 of the FAN1 gene [4]. Here, FAN1 is linked to chronic kidney disease.