Analysis of T cells in tumor tissue revealed a significantly increased percentage of NKp46+ (p = 0.006) and FasL+ (p = 0.003) and a decreased percentage of KLRG1+ (p = 0.01), and PD-1+ (p = 0.009) of CD3+CD49− cells in the metformin-treated group compared to the control group (Figure 4D–G). The gene discussed is KLRG1; the disease is neoplasm.