To further explore the impact of EP on the expression of ECM-degrading enzymes in keloids, we assessed the mRNA expression levels of metalloproteinase I (MMP1), metalloproteinase III (MMP3), and tissue inhibitor of metalloproteinases I (TIMP1) in both TGF-β1-treated HDFs and KFs. This evidence concerns the gene TGFB1 and keloid.