KIM-1 on admission day was also independently able to predict multi-organ dysfunction (SOFA > 12, adjusted OR for CKD, COPD, bilirubin, and platelets 2.24 [1.05–4.78], p = 0.038 and APACHE ≥ 20, adjusted odds ratio 1.94 [1.27–2.96], p = 0.02 per 1 loge KIM-1 increase, respectively). The gene discussed is HAVCR1; the disease is chronic kidney disease.