HAVCR1 and acute liver failure: Interestingly, a later, well-designed publication by the same authors investigated plasma KIM-1 in acetaminophen (APAP) overdose, APAP-induced liver injury, and APAP-induced acute liver failure (ALF) and found that plasma KIM-1 on admission day was superior to creatinine in predicting acute kidney injury in APAP-associated injury and failure [48].