HAVCR1 and Sepsis: Patients with advanced sepsis and multiple organ dysfunction upon admission to the ICU, as determined by a SOFA score > 12 or an APACHE score ≥ 20, had significantly higher KIM-1 serum levels than their counterparts with lower scores (208.2 vs. 344 pg/mL, p = 0.011 and 143.3 vs. 277.3 pg/mL, p = 0.006, Figure 5A,B).