While no association was observed when TNFi were analyzed together, the minor allele of TNF-α-238 (rs361525) was associated with poor response to infliximab (OR: 0.57 [95% CI: 0.34–0.96]) across seven studies including 818 patients with psoriasis [29,37,97,98], or IBD [83,85,102]. This evidence concerns the gene TNF and inflammatory bowel disease.