One study including 80 patients assessed the association between six genetic variants and response to treatment of RA patients with anti-IL-R1 and found three SNPs (IL-1B (+3954) (rs1143634), IL-1A (+4845) (rs17561) and IL-1A (−889) (rs1800587)) across two genes were associated with response to anti-IL-R1 [74] (Supplementary Table S4). Here, IL1A is linked to rheumatoid arthritis.