AGT and multiple sclerosis: Additionally, AngII acts on T cell receptors [51], modulating the immune and inflammatory responses that result in autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis) [52], diseases arising from chronic hyper-inflammation (e.g., atherosclerosis, coronary artery disease and chronic kidney disease) [53,54] and neurodegenerative disorders (e.g., Alzheimer’s disease, multiple sclerosis and motor neuron disease) [55,56].