In this line, ADAMTS2 encodes a procollagen proteinase that plays a crucial role in the cleavage of fibrillar procollagens types I-III and type V [58], involved in the recessively inherited Ehlers–Danlos syndrome type VIIC, which manifest ocular alterations, including glaucoma in a few patients [59,60]. The gene discussed is COL1A2; the disease is glaucoma.