PCDH19 and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: Only one case, Patient 5, initially clinically thought to have Dravet syndrome (she presented fever-triggered seizures in the first year of life, status epilepticus, behavioral problems, and developmental delay after normal infant development), was found to have PCDH19-related familial inheritance and expected phenotypic manifestation based on the pedigree (Figure 3) [16].