On the other hand, Chaicharoenaudomrung et al. (2023) tested in an NK cell line (NK-92) that exposure to COR increased the mRNA expression of genes encoding proinflammatory cytokines such as IL-2, TNF-α, and IFNγ and enhanced their antitumor activity against two cancer cell lines by increasing interferon and granzyme B secretion [91]. Here, TNF is linked to cancer.