Nidogens have been shown to be upregulated in the mesangial matrix and the GBM in glomerular disorders, such as lupus nephritis, IgA nephropathy, and diabetic nephropathy [69,70], but it is a novelty for NID1 to be increased in MCD, presumably as adaptation during FPE. Here, NID1 is linked to IgA glomerulonephritis.