For AD, pTau181 (rho = 0.3, p = 0.001) and NFL (rho = 0.223, p = 0.02) levels were related to tau centiloid, and pTau181 (rho = 0.2295, p = 0.01) level was related to amyloid centiloid. The gene discussed is MAPT; the disease is Alzheimer disease.