S1PR1 and glioblastoma: - Wnt/β-catenin controlled barrier development [105]- expression modulated by Na/K-ATPase [107]- down-regulated by hypoxia/middle cerebral artery occlusion [50]- down (haemorrhage) (PI3K, sphingosine 1-phosphate receptor 1) [104]- loss in EAE, glioblastoma [78]- down-regulated at low Cu [94]