CD36 and hepatocellular carcinoma: For instance, the coculture of CD36+CAFs with HCC cells accelerates tumor progression, while combined treatment with sulfosuccinimidyl oleate (SSO, an irreversible inhibitor of FA translocase CD36 that significantly restrains FA import) and ICI is known to be effective at restoring the immunity of T-cells, partly owing to the poor metabolic flexibility of tumor cells compared to T-cells [45].