Gene PRRX2 can promote the drug resistance of advanced prostate cancer and the malignant phenotype of adenocarcinoma of the lung, while the knockout of PRRX2 can effectively inhibit the proliferation and growth of breast cancer [55,56], which was seen to be downregulated in the comparison between the control and Ba groups. The gene discussed is PRRX2; the disease is Familial prostate cancer.