A disadvantage of the study is the small size of the study groups and the lack of additional data, e.g., BMI values, fasting glucose and insulin levels, total cholesterol, LDL fraction cholesterol, HDL fraction cholesterol, triglyceride levels, androgen hormone levels, in order to draw attention to the fact that cycle disorders may be a prelude to metabolic disorders occurring in women with PCOS. The gene discussed is INS; the disease is polycystic ovary syndrome.