Given that the increased expression of IL-1β, TNF-α, INF-γ, and their combined effect results in an enhanced vulnerability of pancreatic β-cells to autoimmune destruction [36], we asked whether verapamil exposure could protect the MIN6 β-cells from cytotoxic effects of these cytokines in our T1D-Cytomix model. This evidence concerns the gene IL1B and type 1 diabetes mellitus.