CSRP3 and familial dilated cardiomyopathy: In contrast, expression of the MLP-Y66C (HCM) and MLP-K69R (DCM) variants was increased in the membrane- and cytoskeleton-enriched fractions, as well as in the total lysates, compared to MLP-WT (Figure 4A, right and left panels, MLP-Y66C and -K69R vs. MLP-WT).