We applied quantitative PCR to determine the expression of 14 genes including CXCR2, SAA, COX1 and COX2, PPAR-α, -δ and -γ, Gro-α and -γ, IL8, p21, c-myc, CD44 and CSF1 in tumor and adjacent normal mucosa of 21 CRC patients. The gene discussed is CXCL1; the disease is colorectal carcinoma.