CXCL8 and colorectal carcinoma: The approximate fold changes of these genes in CRC patients compared to those of normal subjects were as follows: CD44 (2.28-fold; p < 0.001); IL8 (3.39-fold; p < 0.001); CXCR2 (3.28-fold; p < 0.001) and c-myc (2.03-fold; p = 0.044).