GCG and diabetes mellitus: Figure 1n provides insights into the tissue/body weight ratios, demonstrating that the PAT, iWAT, and eWAT of GCG-intervened db/db mice exhibited significantly higher values compared to those of the db/db model group mice. Conversely, the BAT of db/db model group mice showed significantly higher values than those of the GCG–intervened db/db group mice. These results underscore that GCG treatment contributes to the prevention of weight loss in the later stages of diabetes by preserving adiposity (PAT, iWAT, and eWAT) in db/db mice.