ACHE and Alzheimer disease: For example, Ouattara et al., [70] demonstrated that Nelsonia canescens extracts contain various polyphenolic compounds such as p-coumaric acid, caffeic acid, chlorogenic acid, ferulic acid, gentisic acid, apigenin, luteolin, and quercetin which exhibit anti-AD activity through antioxidant and acetylcholinesterase (AChE) inhibition pathways.