Figure 4a shows that the liver of LFD-fed mice displayed a healthy red hue, while the liver of HFD-fed mice appeared pale and contained fat particles. Notably, dietary supplementation of CPWE could effectively ameliorate HFD-induced fatty liver. Moreover, consistent with the lower liver weight (Figure 4b), H&E histological staining showed that CPWE sufficiently reversed hepatic lipid deposition in HFD-fed mice (Figure 4c). In addition, CPWE also decreased serum ALT (Figure 4d) and AST (Figure 4e) levels. This evidence concerns the gene GPT and fatty liver disease.