When Fer‐1 was co‐treated with DEX on AML‐12 cells, Fer‐1 alleviated the changes in the expression of GSTP1 (p < 0.05), GPX4 (p < 0.05), and TF (p < 0.05) induced by DEX. The gene discussed is GSTP1; the disease is acute myeloid leukemia.