BRCA2 accounts for 50% (7/14), with P/LP variants including a variety of tumors in relatives such as breast, thyroid, bone, gastric, prostate, leukemia, and esophagus, followed by ATM, in 3/14 (21.4%), which referred on thyroid, gastric, and brain cancers. The gene discussed is BRCA2; the disease is leukemia.