Blood tests revealed polyglobulia (Hb 18.9 mg/dL, hematocrit 55.5%), mild thrombocytopenia (128,000/μL), and peripheral blood smear showed erythrocyte anisocytosis, rare platelets (macro thrombocytes and megalothrombocytes), elevated CA 125 (646 U/mL; the normal value < 35 U/ml), neuron-specific enolase (NSE) slightly elevated (18.4 ng/mL; the normal value < 16,3 ng/mL), the other tumor markers (AFP, CA19-9, ACE) being within normal limits. Here, ENO2 is linked to neoplasm.